Matthew P Frosch Selected Research

Disease Progression

4/2013	Spinocerebellar ataxia type 7: clinical course, phenotype-genotype correlations, and neuropathology.
1/2013	Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders.

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Matthew P Frosch Research Topics

Disease

83	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 01/2002
27	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2024 - 02/2004
19	Amyloid Plaque 01/2021 - 02/2002
17	Dementia (Dementias) 08/2023 - 05/2002
13	Tauopathies 05/2024 - 10/2011
13	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 02/2003
12	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2023 - 11/2007
9	Hemorrhage 01/2024 - 11/2008
9	Parkinson Disease (Parkinson's Disease) 01/2022 - 05/2002
7	Cognitive Dysfunction 01/2023 - 01/2012
7	Neoplasms (Cancer) 01/2023 - 02/2010
7	Corticobasal Degeneration 01/2023 - 11/2007
7	Frontotemporal Dementia (Semantic Dementia) 03/2014 - 10/2006
6	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2023 - 11/2007
6	Gliosis 01/2018 - 08/2007
5	Multiple System Atrophy 10/2022 - 11/2015
5	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 02/2010
5	Glioma (Gliomas) 01/2021 - 01/2013
5	Inflammation (Inflammations) 01/2019 - 02/2004
4	Pick Disease of the Brain (Pick's Disease) 05/2024 - 01/2008
4	Cerebral Hemorrhage 04/2020 - 11/2012
4	Hemorrhagic Stroke 11/2015 - 07/2005
3	Hippocampal Sclerosis 01/2023 - 01/2012
3	Atrophy 10/2022 - 01/2008
3	Synucleinopathies 01/2022 - 10/2017
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 01/2008
3	Brain Neoplasms (Brain Tumor) 11/2017 - 02/2012
3	Huntington Disease (Huntington's Disease) 11/2017 - 05/2010
3	Lewy Body Disease (Lewy Body Dementia) 01/2013 - 01/2012
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 10/2022 - 04/2013
2	Cerebellar Ataxia (Dysmetria) 10/2022 - 01/2019
2	Neuroinflammatory Diseases 01/2022 - 11/2015
2	Infections 01/2021 - 08/2011
2	Siderosis 12/2020 - 07/2011
2	Familial Cerebral Amyloid Angiopathy 04/2020 - 11/2008
2	Amyloidosis 01/2019 - 09/2008
2	Myoclonus (Nocturnal Myoclonus) 01/2019 - 01/2016
2	Drug Resistant Epilepsy 01/2016 - 01/2009
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 11/2015 - 06/2008
2	Demyelinating Diseases (Demyelinating Disease) 11/2015 - 06/2008
2	Disease Progression 04/2013 - 01/2013
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2012 - 08/2011
2	Cerebrovascular Trauma 01/2012 - 01/2012
2	Stroke (Strokes) 12/2011 - 06/2010
2	Infarction (Infarctions) 08/2011 - 02/2010
2	Nervous System Diseases (Neurological Disorders) 05/2010 - 11/2005
2	Tuberous Sclerosis (Bourneville's Disease) 12/2009 - 01/2009
1	Normal Pressure Hydrocephalus 11/2023
1	Chordoma 01/2023
1	Autonomic Nervous System Diseases (Dysautonomia) 10/2022

Drug/Important Bio-Agent (IBA)

55	Amyloid (Amyloid Fibrils)IBA 01/2024 - 02/2002
25	Amyloid beta-PeptidesIBA 04/2024 - 01/2002
23	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2003
11	Peptides (Polypeptides)IBA 01/2023 - 12/2003
10	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2024 - 01/2008
8	SynucleinsIBA 04/2024 - 11/2015
8	Biomarkers (Surrogate Marker)IBA 11/2023 - 04/2013
8	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2016
6	ProgranulinsIBA 05/2014 - 01/2009
5	Protein Isoforms (Isoforms)IBA 05/2024 - 10/2006
5	tau Proteins (tau Protein)IBA 05/2024 - 11/2007
5	AntibodiesIBA 01/2023 - 05/2002
5	alpha-SynucleinIBA 10/2022 - 05/2002
4	Presenilin-1IBA 08/2023 - 03/2005
4	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023 - 01/2009
4	Apolipoproteins E (ApoE)IBA 01/2020 - 10/2012
3	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 01/2024 - 01/2017
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 11/2017
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021 - 01/2017
3	LipidsIBA 09/2019 - 10/2017
3	Fatty Acids (Saturated Fatty Acids)IBA 11/2015 - 02/2003
3	UbiquitinIBA 10/2012 - 01/2008
3	Messenger RNA (mRNA)IBA 11/2007 - 05/2006
2	Melanins (Melanin)IBA 01/2024 - 11/2019
2	neuromelaninIBA 01/2024 - 11/2019
2	IronIBA 01/2022 - 12/2020
2	AN-1792IBA 01/2022 - 05/2010
2	Carrier Proteins (Binding Protein)IBA 12/2021 - 01/2019
2	formic acid (formate)IBA 10/2021 - 05/2006
2	FibrinIBA 01/2021 - 01/2019
2	Superoxide Dismutase-1IBA 01/2020 - 11/2010
2	Apolipoprotein E4IBA 01/2020 - 07/2012
2	CytokinesIBA 01/2019 - 11/2015
2	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2017 - 03/2013
2	Matrix Metalloproteinases (MMPs)IBA 11/2015 - 06/2009
2	ApolipoproteinsIBA 09/2014 - 07/2012
2	polyglutamineIBA 04/2013 - 05/2010
2	Coloring Agents (Dyes)IBA 01/2013 - 02/2012
2	thioflavin TIBA 08/2012 - 08/2010
2	PresenilinsIBA 01/2010 - 03/2005
2	Flavin-Adenine Dinucleotide (FAD)IBA 01/2010 - 03/2005
2	trans-sodium crocetinate (crocetin)IBA 12/2009 - 01/2009
2	Insulysin (Insulin-Degrading Enzyme)IBA 12/2003 - 04/2003
1	ORALIT (ORS)IBA 05/2024
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2023
1	Monoclonal AntibodiesIBA 01/2023
1	Nuclear Pore Complex Proteins (Nucleoporins)IBA 01/2023

Therapy/Procedure

9	Therapeutics 05/2024 - 09/2002
3	Immunotherapy 01/2022 - 02/2007
2	Drug Therapy (Chemotherapy) 11/2016 - 05/2016